The Failure of Peer Review (Especially in Medicine)

August 17th, 2017

By Brendan D. Murphy

Guest writer for Wake Up World

“Today Science is up on a pedestal. A new god has appeared; his high priests conduct the rituals, with nuclear reactors, moon-probing rocket ships, cathode tubes and laser beams. And their territory is sacrosanct; laymen are denied entry.” – Bruce Cathie

The defects in the peer review system have been the subject of a profusion of critical editorials and studies in the literature over recent years. The notion of peer review occupies special territory in the world of science. However, investigation of suppressed innovations, inventions, treatments, cures, and so on rapidly reveals that the peer review system is arguably better at one thing above all others: censorship. This can mean censorship of everything from contrarian viewpoints to innovations that render favored dogmas, products, or services obsolete (economic threats) depends on circumstances. The problem is endemic, as many scientists have learned the hard way. The failure of peer review is one of science’s dirty “secrets.”

Peer review is known to engender bias, incompetence, excessive expense, ineffectiveness, and corruption. A surfeit of publications has documented the deficiencies of this system. – Dr David Kaplan [1]

Australian physicist Brian Martin elaborates in his excellent article Strategies for Dissenting Scientists:

Certain sorts of innovation are welcome in science, when they fall within established frameworks and do not threaten vested interests. But aside from this sort of routine innovation, science has many similarities to systems of dogma. Dissenters are not welcome. They are ignored, rejected, and sometimes attacked.[2]

Electric Universe researcher Wal Thornhill stated plainly in our GFM Media interview that the peer review system amounts to censorship. Fellow independent scientist Gary Novak is also scathing, stating:

“Peer review is a form of censorship, which is tyranny over the mind. Censorship does not purify; it corrupts… There is a lot of junk science and trash that goes through the peer review process.”[3]

Martin asks:

“What do [scientists] have to gain by spending time helping an outsider? Most likely, the alleged discovery will turn out to be pointless or wrong from the standard point of view. If the outsider has made a genuine discovery, that means the outsider would win rewards at the expense of those already in the field who have invested years of effort in the conventional ideas.”[4]

The Problem of “Experts”

Scientists in particular are prone to being cathected to their pet theories and opinions, especially if they have been visibly rewarded or publicly obtained accolades as a result. Scientists, just like laypeople, have susceptible emotional bodies and often fairly hefty egos—partially due to their “expertise” and academic titles, qualifications, theories, etc.

Dr Malcolm Kendrick comments in Doctoring Data that, “by definition, anyone who is an ‘expert’ in an area of medicine will be a supporter of whatever dogma holds sway.”[5] Close study of power dynamics in medicine bears this out.

Consider the following words from The Lancet’s editor Richard Horton:

“The mistake, of course, is to have thought that peer review was any more than a crude means of discovering the acceptability—not the validity—of a new finding…We portray peer review to the public as a quasi-sacred process that helps to make science our most objective truth teller. But we know that the system of peer review is biased, unjust, unaccountable, incomplete, easily fixed, often insulting, usually ignorant, occasionally foolish, and frequently wrong.”[6]

Peer review, as a “quasi-sacred” process that somehow supposedly transcends the foibles and follies human nature has taken on sacred ritual status. Has the paper been blessed by the Peer Review Priest? Peer review is held to be more than just useful and functional (which clearly it is not, generally speaking)—it is held as a transcendent, almost magical, organizing force occurring in the heavenly ivory towers of Science, which somehow avoids falling prey to human weaknesses by virtue of those humans’ lofty qualifications as “scientists.”

Scientists, of course, aren’t quite human—they are something more, something pure, something that the layman can never be. Students undergo a magical alchemical process as they proceed through educational institutions and emerge transformed from their chrysalis with their doctorates, masters, stethoscopes and equations. They are the Chosen Ones, the purified, the holy, the saved, the righteous.

It is clear, however, that not only is the popular view of peer review misleading, but the most prestigious publications are some of the very worst offenders. Significant scientific publications—for example, the journal Nature—have a well documented history of prejudice against findings or hypotheses that run contrary to established scientific dogma.

Writing in the British Medical Journal (BMJ) in May 2000, Canadian-based researcher, David Sackett, said that he would “never again lecture, write, or referee anything to do with evidence based clinical practice,” over his concern that “experts” are stifling new ideas.  He wants the retirement of experts to be made compulsory.

Sackett says that “…progress towards the truth is impaired in the presence of an expert.”[7]

Trusting “experts” in oncology, for example, is generally a very good way to artificially speed one’s trip to the grave, particularly if one has metastatic cancer. (See The Truth About Chemotherapy – History, Effects and Natural Alternatives.) And yet “Experts” are now on a rarified level that perhaps only celebrities can understand—they are virtually demigods today.

In the main, “experts” are those people in the establishment who espouse the mainstream dogma and reify the politically correct belief structures. “Experts” are lionized because the world that made them experts promotes and validates them when they affirm the already established beliefs—and the media is complicit in this. If you want to be horribly misled on any number of important issues, just head straight to the TV and listen to the establishment’s “experts.”

Is Most Research Just Bullshit?

Harvard Medical School’s Dr. Marcia Angell is the former Editor-in-Chief at the New England Journal of Medicine, where she spent twenty years poring over scientific papers, saturated in the dubious practices that pervade the world of medical research. She states bluntly:

“It is simply no longer possible to believe much of the clinical research that is published, or to rely on the judgment of trusted physicians or authoritative medical guidelines. I take no pleasure in this conclusion, which I reached slowly and reluctantly over my two decades as an editor of The New England Journal of Medicine.”[8]

Most “experts” in medicine are, psychologically speaking, simply engaged in well-paid groupthink and confirmation bias exercises, vigorously affirming and defending their ego’s construction of the world. Medicine and, science in general, to paraphrase physicist Max Planck “advances one funeral at a time.”

Once the public has accepted the scientific establishment’s truths, narratives, and designated “experts” then researchers whose research yields results deviating from the accepted norm can be immediately branded as crackpots, lunatics, fringe nuts, pseudo-scientists and so on, regardless of how meticulous their methods, and irrefutable their results. The media is crucial in this control dynamic because it sells the establishment’s reality. Thus is the politically correct status quo maintained.

Peer “Review” Lets Garbage Through—and Lots of it!

“Peer review” censorship exemplifies the neophobia in the world of science which serves to protect the status quo rather than improve knowledge by weeding out dubious epistemologies and results, as it is meant to. This supposed mechanism of “quality control” has resulted not only in the dismissal of much important and credible research, but it has also let fraudulent research –and lots of it!—be published at the same time. Papers that appear to support fashionable ideas or entrenched dogmas are likely to fare well.

David Kaplan, a professor of pathology at the Case Western Reserve University School of Medicine in Cleveland, has stated that,

“Peer review is broken. It needs to be overhauled, not just tinkered with. The incentives should be changed so that: authors are more satisfied and more likely to produce better work, the reviewing is more transparent and honest, and journals do not have to manage an unwieldy and corrupt system that produces disaffection and misses out on innovation.”[9]

Is it any wonder that John Ionnidis reported in his famous 2005 paper: “Most research findings are false for most research designs and for most fields.” Given the already outlined problems, is it really surprising that, in Ionnidis words, “Claimed research findings may often be simply accurate measures of the prevailing bias”?[10]

Dr. Marc Girard, a mathematician and physician who serves on the editorial board of Medicine Veritas (The Journal of Medical Truth), has written,

“The reason for this disaster is too clear: the power of money. In academic institutions, the current dynamics of research is more favourable to the ability of getting grants—collecting money and spending it—than to scientific imagination or creativity.”[11]

In general, peer reviewers—generally not time-rich—don’t try to replicate experiments and rarely even request the raw data supporting a paper’s conclusions. Peer review is, according to Richard Smith writing in Peer review in health sciences,

“… thought to be slow, expensive, profligate of academic time, highly subjective, prone to bias, easily abused, poor at detecting gross defects, and almost useless for detecting fraud.”[12] (emphasis added)

What about fake peer review? Berlin-based Springer Nature, who publishes the aforementioned Nature journal announced the retraction of 64 articles in 10 journals in an August 18th statement in 2015. This followed an internal investigation which found fabricated peer-review write-ups linked to the articles.

The purge followed similar discoveries of “fake peer review” by several other major publishers, including London-based BioMed Central, an arm of Springer, which began retracting 43 articles in March citing “reviews from fabricated reviewers”.[13]

Yes, that means reviewers that don’t exist—recommended as “reviewers” by the people submitting their work for review. Imagine writing a paper and being able to nominate a non-existent person to review your work, and the contact email supplied to the publisher for this purpose is actually one you made up, which routes the paper back to you (unbeknownst to the publisher), so that you can then secretly carry out a (favourable) review of your own work under a pseudonym!

In response to fake peer review some publishers have actually ended the practice of author-suggested reviewers.[14]

And now for the Conceptual Penis…

Recently two scientists performed a brilliant Sokal-style hoax on the journal Cogent Social Sciences. Under the pen names “Jamie Lindsay” and “Peter Boyle,” and writing for the fictitious “Southeast Independent Social Research Group,” Peter Boghossian and James Lindsay wrote a deliberately absurd paper loosely composed in the style of “post-structuralist discursive gender theory”—what exactly that is they made no attempt to find out. The authors tell us:

“The paper was ridiculous by intention, essentially arguing that penises shouldn’t be thought of as male genital organs but as damaging social constructions…We assumed that if we were merely clear in our moral implications that maleness is intrinsically bad and that the penis is somehow at the root of it, we could get the paper published in a respectable journal.”[15]

And they did. After completing the paper, and being unable to identify what it was actually about, it was deemed a success and ready for submission, which went ahead in April 2017. It was published the next month after some editorial feedback and additional tweaking. To illustrate how deliberately absurd the paper is, a quote is in order:

“We conclude that penises are not best understood as the male sexual organ, or as a male reproductive organ, but instead as an enacted social construct that is both damaging and problematic for society and future generations… and is the conceptual driver behind much of climate change.”[16]

In plain English, they (seemingly) argued here that a penis is not a male sexual organ but a social construct; the “conceptual penis” is problematic for “gender (and reproductive) identity,” as well as being the “conceptual” driver of climate change. No, really. How this ever got published is something to ponder. The paper is filled with meaningless jargon, arrant nonsense, and references to fake papers and authors. As part of the hoax, none of the sources that were cited were even read by the hoaxers. As Boghossian and Lindsay point out, it never should have been published. No one—not even Boghossian and Lindsay, quoted below—knows what it is actually saying.

“Almost a third of the sources cited in the original version of the paper point to fake sources, such as created by Postmodern Generator, making mock of how absurdly easy it is to execute this kind of hoax, especially, the authors add, in “‘academic’ fields corrupted by postmodernism.” [17] 

The Spectacular Success of Hoax Papers and Non-Existent Authors

In April 2010, Cyril Labbé of Joseph Fourier University in Grenoble, France, used a computer program called SCIgen to create 102 fake papers under the pseudonym of Ike Antkare. SCIgen was created in 2005 by researchers at MIT in Cambridge in order to demonstrate that conferences would accept such nonsense…as well as to amuse themselves. Labbé added the bogus papers to the Google Scholar database, which boosted Ike Antkare’s h-index, a measure of published output, to 94 — at the time, making Antkare the world’s 21st most highly cited scientist.[18]

So a non-existent scientist has achieved the distinction of being one of the world’s most highly cited authors—while “authoring” papers consisting of utter gibberish. Congratulations are certainly in order. In February 2014 it was reported that Springer and the Institute of Electrical and Electronic Engineers (IEEE), were removing over 120 such bogus papers from their subscription services after Labbe identified them using his own software.

Going back at least as far as 1996 journalists and researchers have been getting spoof papers published in conferences or journals to deliberately expose weaknesses in academic quality controls. “Physicist Alan Sokal (of the famous Sokal Affair) succeeded in the journal Social Text in 1996,” while Harvard science journalist John Bohannon revealed in a 2013 issue of Science that he had duped over 150 open-access journals into publishing “a deliberately flawed study.”[19] Bohannon organized submission of the flawed study (technically, many different but very similar variations of the study) to 304 open access journals worldwide over a period of 10 months. 255 went through the whole editing process to the point of either acceptance or rejection.

He wrote:

“Any reviewer with more than a high-school knowledge of chemistry and the ability to understand a basic data plot should have spotted the paper’s shortcomings immediately. Its experiments are so hopelessly flawed that the results are meaningless.”[20]

The hoax paper was accepted by a whopping 157 of the journals and rejected by only 98. Of the 106 journals that did conduct peer review, 70% accepted the paper…[21]

Continues Novak,

“If peer review were open and accountable, there might be a small chance of correcting some of the corruptions through truth and criticism; but the process is cloaked in the darkness of anonymity… Due to the exploitive and corrupt process, nearly everything in science has official errors within it… a culture of protecting and exploiting the errors creates an official reality which cannot be opposed.”[22]

Returning specifically to the arena of medicine, a quote in PLoS Medicine, states:

“Journals have devolved into information laundering operations for the pharmaceutical industry”, wrote Richard Horton, editor of the Lancet, in March 2004. In the same year, Marcia Angell, former editor of the New England Journal of Medicine, lambasted the industry for becoming “primarily a marketing machine” and co-opting “every institution that might stand in its way”… Jerry Kassirer, another former editor of the New England Journal of Medicine, argues that the industry has deflected the moral compasses of many physicians, and the editors of PLoS Medicine have declared that they will not become “part of the cycle of dependency…between journals and the pharmaceutical industry”.[23]

In the words of John Ionnidis, “Most scientific studies are wrong, and they are wrong because scientists are interested in funding and careers rather than truth.”[24]

Clearly the problem of corruption and conflicts of interest have been increasingly on the radar or professional academics for some time now, so much so that it has been the subject of an increasing number of harshly critical articles and editorials. Conveying the depth and breadth of deception to the “uninitiated,” however, presents a unique challenge. And it isn’t just conflict of interest and corruption to blame for the failure of peer review, there is human bias, shoddy review work, fake reviewers and fraud, and varying other human interests to factor in.

At the very least we need to cease indoctrinating students into the dogma that all good things have been peer reviewed, and the converse: anything that has not been peer reviewed is clearly blasphemous and crafted by the hands of sinners.

I can’t help but cringe when I hear people ask if a study has been “peer-reviewed”—the response it most often deserves is simply, “Who cares?”

“The case against science is straightforward: much of the scientific literature, perhaps half, may simply be untrue. … In their quest for telling a compelling story, scientists too often sculpt data to fit their preferred theory of the world. Or they retrofit hypotheses to fit their data. … Afflicted by studies with small sample sizes, tiny effects, invalid exploratory analyses, and flagrant conflicts of interest, together with an obsession for pursuing fashionable trends of dubious importance, science has taken a turn towards darkness.”

– Richard Horton, editor of The Lancet, “Offline: What is medicine’s 5 sigma?”, The Lancet, 11 April 2015.

The Failure of Peer Review (Especially in Medicine) — with Brendan D. Murphy

References:

• [1] David Kaplan, How to fix peer review, http://www.newmediaexplorer.org/sepp/2004/01/29/peer_review_politics_of_science.htm
• [2] Brian Martin, Strategies for Dissenting Scientists, Journal of Scientific Exploration, Vol. 12, No. 4, 1998, pp. 605-616.
• [3] Gary Novak, Peer Review is Broken, http://nov55.com/prv.html
• [4] Martin, op. cit.
• [5] Kendrick, 133.
• [6] Richard Horton, “Genetically modified food: Consternation, confusion, and crack-up,” The Medical journal of Australia, 172 (4), 2000.
• [7] Too  many experts spoil the science, http://www.abc.net.au/science/news/health/HealthRepublish_124166.htm
• [8] Marcia Angell, Drug Companies & Doctors: A Story of Corruptionhttp://www.nybooks.com/articles/2009/01/15/drug-companies-doctorsa-story-of-corruption/
• [9] David Kaplan, How to fix peer review, http://www.newmediaexplorer.org/sepp/2004/01/29/peer_review_politics_of_science.htm
• [10] John Ionnidis, Why Most Published Research Findings Are False, PLoS Medicine, August 2005
• [11] Marc Girard, http://www.laleva.org/eng/2006/02/false_medical_research_shows_up_systemic_flaws.html
• [12] http://www.peere.org/wp-content/uploads/2016/05/Willis.pdf
• [13] Ewen Callaway, Faked peer reviews prompt 64 retractions, http://www.nature.com/news/publishers-withdraw-more-than-120-gibberish-papers-1.14763
• [14] Ibid.
• [15] Peter Boghossian, Ed.D. (aka Peter Boyle, Ed.D.) and James Lindsay, Ph.D. (aka, Jamie Lindsay, Ph.D.), The Conceptual Penis as a Social Construct: A Sokal-Style Hoax on Gender Studies, http://www.skeptic.com/reading_room/conceptual-penis-social-contruct-sokal-style-hoax-on-gender-studies/#.WR_ysma0ssk.facebook
• [16] Ibid.
• [17] Ibid.
• [18] Richard Van Noorden, Publishers withdraw more than 120 gibberish papers, https://www.nature.com/news/publishers-withdraw-more-than-120-gibberish-papers-1.14763
• [19] Ibid.
• [20] Hundreds of open access journals accept fake science paper, https://www.theguardian.com/higher-education-network/2013/oct/04/open-access-journals-fake-paper
• [21] Ibid.
• [22] Novak, op.cit.
• [23] Richard Smith, Medical Journals Are an Extension of the Marketing Arm of Pharmaceutical Companies, http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0020138
• [24] Ionnidis, op. cit.

About the author:

Critically acclaimed author and co-founder of Global Freedom Movement, Brendan D. Murphy is a leading expositor of the new paradigm of integrated science and spirituality/sovereignty. He is a passionate advocate of accelerated conscious evolution through sound-based DNA/kundalini activation and intentional harnessing of the life-supporting (negentropic) aetheric forces of consciousness, while also having experience in psychoenergetic and belief change modalities.

For Brendan, compassionately hacking the Matrix is more than just sport, it’s a way of life. He lives and breathes it, taking a stand for truth and beckoning others to join him on the path of informed, compassionate, and courageous living. Understanding that the outer world always holographically reflects the inner, Brendan believes idle research and information absorption is not enough — we must embody our ideals now and transmute knowledge into wisdom through willful and gutsy application.

“Enough of the slave species legacy we’ve been playing out for millennia! It’s time to rediscover sovereignty, infinite consciousness and our multi-dimensional selves. Evolution is calling. Will we answer?”